The treatment of gangrene mainly includes the following methods. For mild cases, debridement of necrotic tissue and proper antibiotic treatment are often used. In severe cases, especially when wet gangrene is accompanied by systemic symptoms, surgical amputation may be necessary. In addition, improving blood circulation is crucial. This can be achieved through medications that promote blood flow and proper physical therapy. At the same time, controlling underlying diseases such as diabetes is also important to prevent the progression of gangrene.